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SK Biopharmaceuticals, BIORCHESTRA collaborate to develop miRNA-targeted therapeutics

2022.01.05
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SK Biopharmaceuticals, BIORCHESTRA collaborate to develop miRNA-targeted therapeutics

 

SK Biopharmaceuticals, BIORCHESTRA forge ties to research and develop new compounds for potential anti-seizure medication

 

SK Biopharmaceuticals obtains joint ownership of intellectual property and licensing rights to future candidates, and seeks to expand target indications for various central nervous system diseases

 

South Korea, Jan. 5, 2022 – SK Biopharmaceuticals and BIORCHESTRA announced today that they have forged a partnership to research and develop new therapeutic compounds targeting microRNAs[1] (miRNA) for a potential treatment of epilepsy.

 

Under the collaboration agreement, BIORCHESTRA, a South Korea-based privately-held biotech company that develops RNA therapeutics for neurodegenerative diseases, will be responsible for target discovery, selection, and synthesis via its in-house technology.

 

BIORCHESTRA has a platform using antisense oligonucleotides[2] (ASO) to inhibit and regulate miRNA function, and a proprietary drug delivery system (BDDSTM) that penetrates the blood-brain barrier (BBB) and delivers RNA drugs to the brain.

 

SK Biopharmaceuticals, a global innovative pharmaceutical company, will validate disease-modifying targets, as well as carry out preclinical studies.

 

The two companies will also jointly own intellectual property and licensing rights to compounds discovered and developed through their research collaboration, while SK Biopharmaceuticals will seek to expand target indications with the compounds for various central nervous system diseases.

 

Branden Ryu, CEO of BIORCHESTRA, said: “Our collaboration with SK Biopharmaceuticals will help us tap into our new partner’s expertise in drug development. We hope to accelerate the discovery and development of potential compounds for patients with CNS diseases.”

 

Jeong Woo Cho, PhD, President and CEO of SK Biopharmaceuticals, said: “SK Biopharmaceuticals is continuously expanding modality to create the next generation of therapeutics. We will further pioneer a new approach to drug discovery for patients through innovation and partnerships, including with BIORECHSTRA.”

 

About SK Biopharmaceuticals

SK Biopharmaceuticals and its U.S. subsidiary SK life science are global pharmaceutical companies focused on the research, development and commercialization of treatments for disorders of the central nervous system (CNS). The companies have a pipeline of eight compounds in development for the treatment of CNS disorders, including epilepsy. Additionally, SK Biopharmaceuticals is focused on early research in oncology. For more information, visit SK Biopharmaceuticals’ website at www.skbp.com/eng and SK life science’s website at www.SKLifeScienceInc.com

 

About BIORCHESTRA

BIORCHESTRA is an emerging biotech in Korea. Its lead program, BMD-001, shows disease-modifying potential for treatment of neurodegenerative diseases by targeting a specific miRNA. BIORCHESTRA has been selected as the first awardee of J&J’s Innovation Quick Fire Challenge on Neuroscience in June, 2021. Destum Partners, a U.S.-based advisory and consulting firm for the biopharmaceutical and life sciences industries, is BIORECHSTRA's advisor. For more information, visit BIORCHESTRA’s website at http://biorchestra.com/.

 

 

Media contacts :

SK Biopharmaceuticals

Hyongki Park, head of communications

Jaehee Kang, communications manager

skbp_comm@sk.com

 

BIORCHESTRA

HyeJeong Yoon, head of business development

hyejeong.yoon@biorchestra.com

Yein Song, business development manager

 

 

[1] miRNAs are a class of noncoding RNA that regulate post-transcriptional gene expression via translational repression. miRNAs are gaining attention as a novel target for diagnosis and treatment of various diseases. Front. Endocrinol., 03 August 2018 | https://doi.org/10.3389/fendo.2018.00402

[2] Antisense oligonucleotides (ASO) are short, synthetic, single-stranded oligodeoxynucleotides that can alter RNA and reduce, restore, or modify protein expression through several distinct mechanisms. Rinaldi, C., Wood, M. Antisense oligonucleotides: the next frontier for treatment of neurological disorders. Nat Rev Neurol 14, 9–21 (2018). https://doi.org/10.1038/nrneurol.2017.148

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SK Biopharmaceuticals Co., Ltd. Privacy Policy

SK Biopharmaceuticals Co., Ltd. (“Company”) is dedicated to complying with privacy regulations in pursuant of applicable laws and committed to protecting your privacy and personal information by setting a privacy policy in compliance with applicable laws. The Company may, in its discretion, amend this Privacy Policy according to changes in applicable laws and management.

1. Collection, Purpose, and Use of Personal Information

The Company collects only the minimum amount of personal information required to provide our services, and the collected personal information will only be used for the purposes stated in this policy. Your personal information is not used for any other purposes or disclosed to an outside source without prior authorization.

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2. Disclosure of Personal Information to Third Party

The Company uses the provided personal information only for the purposes stated in Article 1, and does not use your personal information or disclose such information to a third party without prior authorization. However, exceptions are provided if Company receives disclosure requests in accordance with procedures designated by the law. The following are examples of such exceptions.

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The Company immediately destroys personal information a year after achieving the purpose of collection. However, if storage is necessary in accordance with applicable laws, the Company may store personal information for a period of time required by such law.

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The Company has established and is operating the following technical and managerial security measures to ensure that the collected personal information is not lost, stolen, leaked, falsified, or damaged.

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2. Technical Security Measures

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To protect the personal information provided to us and handle complaints and inquiries from information providers regarding their personal information, the Company has designated the following department and representative in charge of protecting personal information.

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8. Amendment and Notice of Privacy Policy

1. This Privacy Policy takes effect starting July 1, 2018.

2. In the event of any future addition, deletion, revision, and such amendments to the privacy policy following changes in applicable laws or security technology, the Company will notify the purpose and contents of the amendment on the Company’s website at least a week prior to enacting the amended privacy policy.

Date of notice and enactment: July 1, 2018